This question is a bit of a "trick" because there is only one Amazon River, but it is composed of thousands of tributaries. The "biggest" part of the system is the Main Stem of the Amazon, which is the largest river in the world by water volume, discharging roughly 209,000 cubic meters per second into the Atlantic. However, if you are looking for the "biggest" tributary, that would be the Rio Madeira, which is nearly 3,300 km long and is a massive river in its own right. In 2026, the Amazon remains the primary "artery" of the South American rainforest, and its "size" is so vast that it accounts for approximately 20% of the total river water that enters the Earth's oceans. For 2026 eco-tourists, the "biggest" experience is often found at the "Meeting of the Waters" near Manaus, where the dark Rio Negro and the sandy Rio Solimões (the upper Amazon) flow side-by-side for several miles without mixing, showcasing the sheer scale and diversity of the world's most powerful river system.