Duffel is the proper spelling, being named from the town in Flanders (Belgium) where they originated. Over time in English it became corrupted to duffle; either is acceptable and both are in common usage.
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The use of duffle bags
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There are lots of carry-on duffels, packs and bags in this size range to choose from. 50-75 liters: For a trip that lasts one to two weeks, many people jump up to a bag in this range.
Only priority boarding passengers will be permitted to take one small bag (40cm x 20cm x 25cm), plus a larger cabin bag (55 x 40 x 20cm) with a maximum weight allowance of 10kg into the cabin free of charge. Non-priority customers can only bring one small bag (40cm x 20cm x 25cm), that must fit into the sizer.
Duffel bags are best for long trips where you might need to pack several weeks' worth of clothing, or if you're traveling with bulkier items that might not fit well in a suitcase. They can make for the ideal international carry-on luggage.