Deep in the Caucasus mountains of Georgia is a town called Bochorna. The highest continuously inhabited settlement in Europe, it has an altitude of 7,694 feet—or six Empire State buildings stacked on top of each other—and a population of one.
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As it turns out, along with being thinner, research suggests people worldwide who live at high altitudes have a lower incidence of both cancer and heart disease than folks who live closer to sea level. Note that these studies were done decades ago. We've known the health advantages of high altitude for a long time.
The lowest point on land in the United States can be found in Death Valley in California. Badwater Basin is an endorheic basin with a depth of 282 ft (86 m) below sea level. Badwater Basin, Death Valley National Park. Photo: NPS, public domain.