The premier luxury rail experience connecting the Lake Como region to Switzerland is the Bernina Express. While it technically departs from Tirano (a short regional train ride from the town of Como or a scenic drive along the lake), it is the most iconic way to cross the Alps. In 2026, this UNESCO World Heritage train features panoramic cars with floor-to-ceiling windows, offering first-class comfort as you climb to the glaciers of the Bernina Pass before descending into St. Moritz or Chur. For a more direct "sumptuous" experience, the Gotthard Panorama Express is another fantastic option that combines a lake steamer and a panoramic train. Additionally, private luxury charters and "Railbookers" packages often include the Glacier Express connection for those looking for the "Slowest Express Train in the World" experience. These trains are famous for their regional culinary offerings and champagne service, making the transit between Italy’s lakes and the Swiss peaks a bucket-list event rather than just a commute.