Fortunately, we now know the answer. It takes an island. A 17th-century Georgian mansion on an island to be exact. The Clooney's will call Sonning-on-Thames in Oxfordshire home now -- a quiet 5.5 acreage about 40 miles west of London, U.K.
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Oodles of A-listers, such as George Clooney, Madonna, Richard Branson, Sylvester Stallone, Gianni Versace, and soccer legend Ronaldinho, own or have owned villas around the shores of Lake Como.
If you can get an open jaw ticket to fly into Rome and out of Milan, then Como is doable, as the train trip from Como to Milan is about an hour. I would agree with the above posters that Amalfi offers more to see and do and I find the coastal just slightly more beautiful than the lakes.
4. Brad Pitt's Villa Costanza. The villa owned by Brad Pitt and Angelina Jolie is a perfect retreat for the couple. Its 18,000 square feet space including 15 rooms and 7 bathrooms is decked with the most luxurious articles.