Isolated from the rest of the planet for 14 million years, Lake Vostok may be the only body of water on Earth to contain no life whatsoever.
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In the Dallol–Danakil area in Ethiopia, researchers found that the hot, saline, and highly acidic ponds found in a volcanic crater are too extreme for life to take hold. Genetic sequencing was used to verify the absence of any organisms. Researchers also found no life in the adjacent brine lakes.