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What pill to take for flying?

People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.



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Pharmacological treatment These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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What medication is used to make flying easier? Common over-the-counter medications used for flying anxiety are Dramamine, Ambien, and Benzodiazepines like Xanax. Natural medications include GABA supplements and Melatonin supplements or gummies.

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Xanax, a member of the same pharmaceutical family (benzodiazepines) as diazepam, is a strong one. Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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Try holding your breath and then breathing deeply, or better still, force yourself to breathe out for as long as you can and then take a long, deep breath. Seif and Farchione both recommended taking deep breaths, since this triggers the calming response and can help to prevent hyperventilation.

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Aspirin? Taking 75mg (a quarter of a normal 300mg tablet) some hours before your flight may reduce your chances of a DVT slightly (but remember that Aspirin can sometimes cause indigestion in people with a tendency to it, if in doubt ask your GP);

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As a general precaution, however, Dr. Varga does not recommend taking either melatonin or a sleeping pill for the first time on a plane, given that both may occasionally cause adverse effects in some people. (And it's best not to find out that you're one of those people while you're trapped at 30,000 feet.)

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If you know you're prone to aviation headaches, take a non-steroidal anti-inflammatory agent (i.e. ibuprofen) one to two hours before takeoff to get ahead of any inflammation or pain.

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Tips to Stay Calm and Comfortable During Your Flight
  1. Let Sleep Calm Your Flighty Nerves. ...
  2. Keep Yourself Distracted On the Plane. ...
  3. Don't Fight the Bumps. ...
  4. Avoid Caffeine When Flying. ...
  5. Listen to Music or Meditate.


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The list of triggers is long: turbulence, take-off, landings, terrorism, crashes, social anxieties, or being too far from home. Some people fear fire, illness spread through the air system, using the toilets, or violence on a plane.

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“Also, some people experience an overall sense of discomfort with the entire flying experience: airport procedures, crowds, turbulence, unappetizing food, cramped space and long flights.” Anxiety is fueled by irrational, worst case scenario thoughts, and confined spaces are breeding grounds for this process.

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Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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Pain Killers and Anti-Febrile Drugs These medications are commonly used to treat pain, fever, or headaches. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and paracetamol may be taken whilst flying.

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These include any hormone-based drugs, like the contraceptive pill and some fertility medicines, and drugs used to prevent heart attack and stroke. Antihistamines should also not be used to help passengers sleep during a flight.

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For Air Travel – Take one 325 mg Aspirin one hour prior to flight and then once a day for 5 days. If on an airplane for more than 3 hours, either walk frequently or do ankle pump exercises (flex your foot up and down repeatedly) in your seat every hour.

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