The show is filmed on location in and around Broken Hill, charting the dramatised lives of the doctors, nurses, pilots and support staff in the Royal Flying Doctor Service as they navigate retrievals across some of the most inhospitable places in the country.

The hit TV drama RFDS (Royal Flying Doctor Service) is primarily filmed in Broken Hill, New South Wales, and across various locations in South Australia. Broken Hill serves as the main hub, with its red-earth landscapes and local airport providing the authentic "outback" setting that defines the show. For the most recent 2025/2026 seasons, production expanded significantly into South Australia, utilizing the Adelaide Studios for interior sets and the Port Augusta RFDS base for operational scenes. Filming also takes place in the stunning Flinders Ranges and the town of Quorn, showcasing the rugged terrain the service actually covers. The production is a major boost for the South Australian economy, injecting over $10 million into the region and utilizing hundreds of local extras to maintain the show's deeply authentic feel for the life-saving work performed by the real-world flight doctors.