For the average tourist in 2026, it is generally recommended to avoid staying deep within the Khlong Toei district (specifically the slum areas) and the "Red Light" hubs like Patpong, Soi Cowboy, or Nana Plaza unless you are specifically looking for that nightlife scene. While these areas are not "dangerous" in terms of violent crime, they can be loud, seedy, and prone to "tourist scams," pickpocketing, and overpriced drinks. Additionally, staying too far from the BTS (Skytrain) or MRT (Metro) lines can make navigating Bangkok’s notorious traffic a daily nightmare. For a first-time visitor, staying in "Old City" (near Khao San Road) might seem iconic, but the lack of rail access means you'll be reliant on taxis and tuk-tuks. Instead, most travelers prefer the safety and convenience of Sukhumvit, Siam, or Riverside. Bangkok is incredibly safe compared to many Western cities, but staying in a "seedy" district can color your perception of the city's otherwise vibrant and friendly culture.