Aside from the monkeys, mammals in the area are generally difficult to spot but include giant anteaters, armadillos, porcupines, three-toed sloths, otters, jaguars, pumas, tapirs, and capybaras.

Angel Falls, located in Venezuela's Canaima National Park, is surrounded by an incredibly biodiverse ecosystem including rainforests, savannas, and the unique flat-top tepuis (table mountains). Due to the isolated nature of the tepui summits, some animal species found there are endemic, meaning they live nowhere else on Earth. Notable residents include the Harpy Eagle, one of the world's most powerful birds of prey, and the vibrant Venezuelan Red Howler Monkey, which can be heard throughout the surrounding canopy. On the ground, you might find Giant Anteaters, Pumas, and Capybaras near the various river systems that feed the falls. The area is also famous for its diverse amphibian life, such as the White-lipped Frog and various species of "Glass Frogs" that thrive in the humid, misty environment created by the 3,212-foot drop. Because the falls are part of the Guiana Highlands, the wildlife is a mix of Amazonian species and unique high-altitude specialists that have adapted to the nutrient-poor soil and dramatic vertical landscapes of the ancient tepui formations.