Which benzodiazepine is best for fear of flying?

The use of psychopharmacologic drugs can aid in the various stages of treatment during exposure therapy. Benzodiazepines, such as clonazepam, help reduce anticipatory anxiety and can enable a patient to manage fear and anxiety during the initial stages of exposure therapy [15].



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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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Flight anxiety medication
  • fluvoxamine (Faverin)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)


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Official answer. Ativan and Xanax are both benzodiazepines used for the treatment of anxiety, and both are equally effective for this use. The differences are: Xanax has a quicker onset of effect, but a shorter duration of action (4 to 6 hours) compared with Ativan's 8 hours.

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Xanax, a member of the same pharmaceutical family (benzodiazepines) as diazepam, is a strong one. Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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What Are the Best—And Safest—Sleeping Pills for Flights?
  • Ambien. Ambien—the most powerful option on this list and the only one that requires a prescription—works as a sedative-hypnotic medication that slows your brain activity to make you feel very sleepy. ...
  • Tylenol PM. ...
  • Melatonin.


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When taken prior to the flight Benzodiazepines such as alprazolam (Xanax), lorazepam (Ativan), clonazepam (Klonopin), and diazepam (Valium) are common options to reduce anxiety of flying. These medications decrease the person's reflective function.

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Try holding your breath and then breathing deeply, or better still, force yourself to breathe out for as long as you can and then take a long, deep breath. Seif and Farchione both recommended taking deep breaths, since this triggers the calming response and can help to prevent hyperventilation.

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Benzodiazepines are only advised for the short-term use for a crisis in generalised anxiety disorder in which case they are not fit to fly.

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Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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Read on for our science-backed strategies* for how to sleep on a plane.
  1. Stay at the right temperature. ...
  2. Wear bed socks. ...
  3. Power down your devices. ...
  4. Wear a light-blocking eye mask. ...
  5. Listen to pink noise. ...
  6. Wear noise-canceling headphones or earplugs. ...
  7. Uncross legs and use footrests. ...
  8. Lean backward with proper support.


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Doctors normally prescribe their anxiety patients with limited doses of . 25mg-0.5mg. While Xanax may be useful for flying on an airplane, it will not help you with your anxiety. It may help in the moment but you will not tackle your fear of flying if you are asleep the whole flight.

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