In 2026, the list of airlines flying nonstop to Spain from North America and major global hubs is extensive, led by Spain's flagship carrier Iberia and its partner American Airlines. From the United States, you can find nonstop service to Madrid (MAD) or Barcelona (BCN) from major gateways like New York (JFK/EWR), Miami, Chicago, Dallas, and Los Angeles. Other major U.S. carriers including Delta Air Lines and United Airlines offer robust seasonal and year-round nonstop routes. From the UK and Europe, low-cost giants like Ryanair, EasyJet, and Vueling dominate the skies, providing nonstop links to nearly every regional Spanish airport including Málaga, Palma de Mallorca, and the Canary Islands. For travelers coming from the Middle East, Emirates, Qatar Airways, and Etihad provide daily nonstop connections to Madrid and Barcelona. If you are looking for a more "boutique" experience, the French all-business-class airline La Compagnie occasionally offers seasonal nonstop flights from Newark to Nice or nearby hubs with easy connections into Spain.