Why does flying weaken your immune system?

While you already know that you'll be around a lot of people at the airport and on the plane, flying also creates environmental conditions that can put your immune system on the defense. The reason? Low humidity.



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Some recent studies do in fact suggest that traveling, especially flying, can have a negative effect on your immune system, thus making it easier for you to get sick.

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Low humidity on airplanes Low humidity can cause the nasal passages to dry out and cause irritation in the nose and throat. On top of that, bacteria and viruses can survive longer in low-humidity environments, making it harder for your body to fight off any infections you might catch aboard a plane.

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The cramped conditions and long periods of being less active on a flight can cause pain, stiffness or swelling of your legs. Being less active can lead to slow blood flow in your veins which increases your risk of developing a blood clot, known as deep vein thrombosis (DVT). DVTs most commonly form in the legs.

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The air pressure while flying increases the risk of blood clots forming, which is not ideal. Heart complications: If you've suffered a heart attack, stroke, cardiac failure or chest pain while at rest, flying should wait. The lower oxygen levels, increased air pressure, high altitude and more could affect your health.

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The main aspect of in-flight health that most of us will encounter is tiredness and changes to circadian rhythms. Flying often involves getting up at unsociable hours, inadequate sleep and messing up the body clock — all of which leave us more susceptible to being hit nastily by any bugs that may be floating about.

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if you suffer from or have had:
  • angina or chest pain at rest.
  • an infectious disease (e.g. chickenpox, flu), including COVID-19.
  • decompression sickness after diving (sometimes called 'the bends')
  • increased pressure in the brain (due to bleeding, injury or infection)
  • infection of your ears or sinuses.
  • recent heart attack.


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Feeling unwell directly after a flight is often the cause of low humidity. Planes have a different atmospheric pressure than we are used to, which can cause the nasal passages to dry, leading to symptoms resembling flu.

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Jet lag is a temporary sleep disorder, but not temporary enough for many travelers. If you're flying from San Francisco to Rome for a 10-day trip, for example, it may take six to nine days to fully recover. That's because it can take up to a day for each time zone crossed for your body to adjust to the local time.

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Planes also have very little humidity and the dry air can irritate the mucous membranes of the throat.

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Jet belly: (noun) the bloated state in which your stomach inflates post-flight. Also, a very unpleasant feeling. May also make you look like you're 3 months pregnant. So how does one prevent this jet belly? Well, it all depends on what you eat on the plane.

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Airborne Illnesses “You are at greater risk if the person is seated within two rows of you. But your risk is lower if the person is seated three or more rows away.” Upper respiratory infections, such as the common cold and the flu, are the most common illnesses that air travelers might be exposed to while in flight.

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Air transportation is a major vehicle for the rapid spread and dissemination of communicable diseases, and there have been a number of reported outbreaks of serious airborne diseases aboard commercial flights including tuberculosis, severe acute respiratory syndrome, influenza, smallpox, and measles, to name a few.

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Common travel-related illnesses include:
  • Diarrheal disease. Most travel-related diarrheal diseases are acquired by consuming contaminated water and food.
  • Hepatitis A. ...
  • Malaria. ...
  • Dengue fever. ...
  • Parasitic infections. ...
  • Tuberculosis. ...
  • Typhoid fever. ...
  • Yellow fever.


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Remember that anything over 6 hours flying time is considered long haul, but flights of longer than 10 hours are not uncommon either. One important thing to remember is to keep your seat belt fastened at all times in case of unexpected turbulence.

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If you don't shower and bacteria and fungi do catch a ride back to your hotel with you, Tetro says you may end up depositing germs that aren't your own into your new space—particularly your bed.

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PLEASE NOTE: You should avoid flying if your nose is congested from a cold or allergies. In the most severe case, this may lead to a permanent decrease in your hearing, prolonged dizziness, or severe pain.

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“If you've got inflammation blocking your means of equalizing the pressure, that's going to hurt,” he said. That pain can continue even after your flight as inflammation prevents the pressure from equalizing, Adalja added. It can also lead to trouble hearing, vertigo, and in rare cases, damage to the eardrum, Wu said.

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