Whether your vape is confiscated depends entirely on how you pack it and where you are going. Per international aviation safety rules, vapes and e-cigarettes containing lithium batteries must be carried in your hand luggage (carry-on). If you place a vape in your checked baggage, it will likely be flagged by security scanners and removed, as the batteries pose a fire risk in the cargo hold. Additionally, any "e-liquid" must comply with the standard 100ml liquid rule and be placed in your clear liquids bag. The biggest risk of total confiscation comes from your destination’s laws. For example, if you are flying to Thailand, Singapore, or India, vapes are strictly illegal; customs officers may seize the device and you could face a heavy fine or even imprisonment. In contrast, in the UK, USA, and most of Europe, they are perfectly legal to transport. Always check the local laws of your transit and arrival countries before you fly. Also, remember that actually using the vape on the plane or in the airport toilets is a serious offense that can lead to arrest and being blacklisted by the airline.