Generally, TSA will not stop you for traveling with common prescription medications, as they are legally permitted in both carry-on and checked luggage. However, for a high-fidelity and hassle-free screening in 2026, you should keep all medications in their original pharmacy packaging with the label clearly showing your name, which must match your passport or ID. If you have "High-Fidelity" medical liquids (like insulin or liquid antibiotics) that exceed the 3.4 oz (100ml) limit, you must declare them to the TSA officer at the start of the screening process; these items are exempt from the standard liquids rule but will undergo additional testing. While TSA is primarily looking for security threats rather than drugs, "controlled substances" or large quantities of unmarked pills may trigger extra scrutiny or a manual bag search. It is a high-fidelity best practice to carry a "Letter of Medical Necessity" from your doctor, especially if traveling with injectable medications or specialized medical devices, to ensure a smooth transition through the checkpoint.