No, in Animal Crossing: New Horizons, villagers will not appear on Mystery Islands if your island has reached its maximum capacity of 10 animal residents. The game's spawning logic requires you to have a fully empty and available plot of land for a "traveling villager" to appear on a Nook Miles Tour. If you fly to a mystery island while your 10 plots are full (even if a current resident is "in boxes" and moving out), the island will be empty of any potential new neighbors. You can only resume "villager hunting" the day after a resident has completely moved away and the plot shows a "For Sale" sign. If your island is full and you want to recruit someone new, your only options in 2026 are to wait for a random visitor to appear at your campsite (who can then be convinced to "kick out" a current resident) or to use an Amiibo card at the Resident Services kiosk to force a specific move-in. Once the "For Sale" sign is active, you have a roughly 24-hour window to find a new villager on a mystery island before the plot is randomly sold to a "void" villager.