Switzerland is within easy reach from Italy. The EuroCity train line has numerous daily connections from Milan to major Swiss cities such as Basel, Berne, Geneva, Lausanne, Lucerne, Lugano and Zurich.
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Many of Trenitalia's Frecciargento AV trains make the daily journey between Milan and Zurich in just 3 hours and 35 minutes, traveling up to 155 miles per hour.
The best way to get from Italy to Switzerland is to fly which takes 1h 59m and costs €100 - €290. Alternatively, you can train, which costs €110 - €320 and takes 7h 17m, you could also bus, which costs €70 - €120 and takes 13h 52m.
Train tickets from Rome to Zurich Hb can start from as little as $49.33 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending the time of day, route and class you book.
Depending on your nationality, you need a visa to travel to Switzerland. Only short-term visa applications (up to 90 days, Schengen visa) such as tourist, visit or business can be submitted online. A visa application can be submitted at the earliest six months before entering the Schengen area.
The simplest way to get from Italy to Switzerland is by train although driving is fine too. I bought a $23 train ticket from raileurope.com to go from Lake Como to Lugano and the ride was a breeze. While my ride took exactly 39 minuets, the quickest route is 25 minutes.
Rome to Switzerland by train. The train journey time between Rome and Switzerland is around 7h 31m and covers a distance of around 815 km. This includes an average layover time of around 1h 2m.
The Bernina Express train route takes you through incredible alpine landscapes and a UNESCO World Heritage Site - it's that amazing. Think of all the clichés about the beauty of scenic train travel and multiply them by 1000. You'll end up on this journey through Switzerland.