Yes, a day trip from Naples to Pompeii is not only possible but is one of the easiest and most popular excursions in Italy. The journey is remarkably short; the Circumvesuviana train departs from Naples' Central Station (Garibaldi) every 30 minutes and reaches the "Pompei Scavi" station—located just steps from the ruins—in approximately 35 to 40 minutes. Because the archeological site is so close to Naples, you can easily arrive at 9:00 AM, spend 4 to 5 hours exploring the ancient streets and villas, and be back in Naples in time for a late lunch or early dinner. While the site is vast, a well-planned 4-hour visit is enough to see the major highlights like the Forum, the Lupanar, and the plaster casts, making it an ideal "low-stress" day trip for those based in the city.