Scuffs and spills happen. Clean your bag's exterior shell and interior nylon lining using a soft, damp cloth, warm water, and mild soap. It'll scrub right up. If the shell of your suitcase picks up a mark that soap and water can't handle, try using a magic eraser to buff it away.
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Whether you have hard or soft luggage, your disinfectant can be the same: hydrogen peroxide or rubbing alcohol. Reichert advises wiping down the entire suitcase with either.
At an airport or hotel, you might be limited to wiping down your soft-sided luggage the same way as you would hard-sided luggage: a wet rag or alcohol wipe. If you can, go one step further with a 1:2 ratio mix of vinegar and water applied to tough stains with an old toothbrush. Wipe and let dry in an open-air spot.
Vinegar falls under the Transportation Security Administration's “3-1-1 liquids rule”, which requires that all liquids and gels in your carry-on luggage be stored in 3.4-ounce (100 ml) or smaller containers — all of which must fit into one quart-sized plastic bag.
Sanitizing Wipes: Wet wipes, in any quantity, can be carried on. This includes baby wipes! Disinfectant sprays: You are allowed to have sprays in your carry-on bag as long as they do not exceed 3.4 oz. Pack larger sizes in your checked luggage.
Disinfectants and Cleaning ProductsMany disinfectants and cleaning products, such as flammable aerosols, certain drain cleaners, oven cleaners, etc. are not allowed in checked or carry-on bags. Many disinfectants and cleaning products contain hazardous chemicals or ingredients.