For a first-time visitor in 2026, three days is generally the ideal amount of time to see Florence’s "Greatest Hits" without feeling completely overwhelmed. A three-day itinerary allows you to dedicate Day 1 to the Duomo and the Accademia (home to Michelangelo’s David), Day 2 to the world-renowned Uffizi Gallery and Ponte Vecchio, and Day 3 to the Pitti Palace and Boboli Gardens on the Oltrarno side of the river. If you are an art historian or want to soak in the atmosphere with long Tuscan lunches, five days is better, as it gives you a buffer for smaller gems like the Bargello Museum or a sunset at Piazzale Michelangelo. Any stay shorter than two days often leads to "museum fatigue," as you'll be rushing through some of the densest collections of Renaissance art in the world.