No, as of 2026, Delta Basic Economy (Fare Class E) tickets are ineligible for all types of upgrades, including paid upgrades, Mileage Upgrade Awards, and Medallion Complimentary Upgrades. This is a core restriction of the Basic Economy product designed to segment the market. Even if you hold top-tier Diamond Medallion status or own a Delta SkyMiles Reserve card, you will not be added to the upgrade list if you are flying on a Basic Economy ticket. Furthermore, these tickets do not earn SkyMiles or count toward Medallion Status (MQDs). If you realize after booking that you need more comfort, your only option is to "cancel" the Basic Economy ticket (subject to a cancellation fee of $99–$199 in 2026) and use the remaining eCredit to purchase a Main Cabin ticket, which is the lowest fare class that allows for upgrades. Once you are in Main Cabin, you can use the "Seat Map" in the Delta app to purchase a move to Comfort+ or First Class if seats are available.