No, Route 66 and I-40 are not the same thing, although they follow a very similar east-west path across the United States. Route 66, known as the "Mother Road," was established in 1926 as a two-lane highway connecting Chicago to Los Angeles, winding through small towns and local main streets. Interstate 40 (I-40) is a modern, high-speed multi-lane freeway that was built as part of the Eisenhower Interstate System to bypass those small towns and provide faster travel. In many parts of the Southwest (particularly in Oklahoma, Texas, New Mexico, and Arizona), I-40 was built directly on top of or parallel to the old Route 66. Because of this, Route 66 was officially decommissioned in 1985. Today, travelers can still find "Historic Route 66" segments that loop away from I-40, taking you through iconic spots like Seligman, Arizona, or the Midpoint Cafe in Texas. While I-40 is the road you take for efficiency, Route 66 is the "scenic" road you take for nostalgia, kitschy roadside attractions, and a glimpse into mid-century Americana.