Should I take an aspirin before I fly?

Talk to your doctor about wearing compression stockings or taking medicine before departure if you have additional risk factors for blood clots. Taking aspirin to prevent blood clots when traveling is not recommended. If you take aspirin for other reasons, check with your doctor.



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Aspirin and medicines such as ibuprofen (Motrin IB, Advil, others) and naproxen sodium (Aleve) may thin the blood. This can decrease blood clotting. Regular use of ibuprofen and naproxen sodium can increase bleeding risks. The medicines, as well as aspirin, also can lead to stomach ulcers.

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Taking aspirin to prevent blood clots when traveling is not recommended. If you take aspirin for other reasons, check with your doctor.

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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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These include any hormone-based drugs, like the contraceptive pill and some fertility medicines, and drugs used to prevent heart attack and stroke. Antihistamines should also not be used to help passengers sleep during a flight.

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Research has shown that wearing compression socks during long-haul flights can significantly reduce the risk of developing blood clots and alleviate symptoms of leg fatigue and discomfort.

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Take pain medication in your carry-on. If you have mild to moderate pain, an Advil or Tylenol may do the trick. If you take prescription pain medication, you may want to talk to your doctor about whether you will need to take a higher dose or augment your existing medication with another drug while traveling.

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Tips for improving blood circulation on a plane
  • Wear compression socks. Compression socks work wonders on the plane! ...
  • Keep hydrated. Staying hydrated is essential for keeping your blood circulation in top shape, especially during a flight. ...
  • Wear loose clothing. ...
  • Choose a seat with additional legroom. ...
  • Improve your fitness.


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For people with vein disease (venous insufficiency), traveling short distances isn't usually problematic. But on a plane or car trip lasting several hours, the risk of blood clots, or deep vein thrombosis (DVT) increases.

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