Should you take a blood thinner before a long flight?

Bajakian recommends you talk to your doctor before taking a flight longer than 4 to 6 hours. In some extremely high-risk cases, she may prescribe a course of low-dose anticoagulation medication for travel.



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Prevent Blood Clots During Travel
  1. Stand up or walk occasionally. ...
  2. Exercise your calf muscles and stretch your legs while you're sitting. ...
  3. Talk to your doctor about wearing compression stockings or taking medicine before departure if you have additional risk factors for blood clots.


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Even if you travel a long distance, the risk of developing a blood clot is generally very small. Your level of risk depends on the duration of travel as well as whether you have any other risks for blood clots.

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After the flight If you have travelled by air you should be alert for the symptoms of DVT for up to one month after flying, and should seek medical help if any symptoms such as a swollen or painful leg, especially the calf, and/or breathing difficulties occur.

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Blood clots can sometimes form in your legs during air travel because you are immobile for long periods of time, often sitting in cramped spaces with little leg room. The clinical term for this type of blood clot is deep vein thrombosis (DVT). The longer the flight, the more at risk you are for developing a clot.

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Tips for improving blood circulation on a plane
  • Wear compression socks. Compression socks work wonders on the plane! ...
  • Keep hydrated. Staying hydrated is essential for keeping your blood circulation in top shape, especially during a flight. ...
  • Wear loose clothing. ...
  • Choose a seat with additional legroom. ...
  • Improve your fitness.


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Your GP will not be able to advise on the use of anticoagulants for flying as it is a specialist issue, so allow plenty of time to get an opinion from your specialist. Note: aspirin is not used to prevent DVT.

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Just as water doesn't flow easily through a kinked-up garden hose, blood can't flow as well through a vein that has a kink. On top of that, changes in air pressure inside the airplane cabin cut down the amount of oxygen you breathe in. Low oxygen in your blood can also make blood clots more likely to form.

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Over-the-counter medicines
  • Diarrhea medicine (Imodium or Pepto-Bismol)
  • Antacid.
  • Antihistamine.
  • Motion sickness medicine.
  • Cough drops, cough suppressant, or expectorant.
  • Decongestant.
  • Pain and fever medicine (acetaminophen, aspirin, or ibuprofen)
  • Mild laxative.


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These include any hormone-based drugs, like the contraceptive pill and some fertility medicines, and drugs used to prevent heart attack and stroke. Antihistamines should also not be used to help passengers sleep during a flight.

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Blood clots can sometimes form in your legs during air travel because you are immobile for long periods of time, often sitting in cramped spaces with little leg room. The clinical term for this type of blood clot is deep vein thrombosis (DVT). The longer the flight, the more at risk you are for developing a clot.

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