Fatigue, Sleep, and Mental Health The FAHS found an increased prevalence of adverse sleep and mental health outcomes such as anxiety, depression, and alcohol abuse among flight attendants (13). Fatigue and depression are symptoms that often coexist (35,36).

Working as cabin crew carries several long-term physiological and psychological side effects due to the extreme environment and irregular nature of the job. Occupational health studies in 2026 highlight that chronic desynchronosis, or "circadian misalignment," often leads to severe sleep disturbances, fatigue (reported by nearly 90% of crew), and metabolic imbalances. Female crew members are particularly susceptible to endocrine disruption and reproductive concerns linked to cosmic radiation exposure and shift work. Furthermore, the low-humidity cabin air causes chronic dehydration and "jet lag skin," while the frequent pressure changes can lead to barotrauma in the ears and sinuses. Psychologically, the job is linked to higher rates of anxiety and depression, stemming from social isolation and the physical toll of constant time-zone transitions.