All cruise lines are subject to strict monitoring by the CDC's Vessel Sanitation Program (VSP) to prevent outbreaks of bacteria, most notably Legionella (the cause of Legionnaires' disease) and E. coli. While no specific line is "known" for having bacteria, Grand Circle Cruise Line and Princess Cruises have both faced high-profile investigations in recent years regarding Legionella detections in their water systems. Legionella thrives in complex plumbing systems and hot tubs if chlorine levels are not meticulously maintained. In 2026, cruise ships use advanced automated chlorination and UV filtration systems to sanitize every drop of water used for drinking, showering, and pools. If a ship fails a CDC inspection (which are unannounced), the results are made public on the CDC "Green Sheet." For travelers, the risk of waterborne bacteria on a modern cruise ship is statistically much lower than in many land-based hotels, as ships are required to test their water chemistry multiple times a day and undergo rigorous deep-cleaning of their holding tanks during dry-dock periods to prevent the buildup of "biofilm" where bacteria could hide.