The airline has maintained a strong safety record throughout its history. It has stringent safety protocols and procedures in place to ensure the well-being of its passengers and crew. According to Airline Ratings, Lufthansa's safety rating is 7/7.

Lufthansa maintains one of the strongest safety records in the aviation industry as of 2026. It consistently ranks in the "Top 20 Safest Airlines" globally by AirlineRatings.com, cited for its rigorous German engineering standards and pilot training programs. The airline has not suffered a fatal passenger jet hull-loss accident in over 30 years (the last being in 1993). While its low-cost subsidiary, Germanwings, suffered a high-profile tragedy in 2015, the core Lufthansa mainline brand has remained a gold standard for operational safety. In 2026, Lufthansa continues to lead in safety innovation, being one of the first major carriers to implement AI-enhanced predictive maintenance, which identifies potential mechanical issues in engines like the Trent XWB before they become safety hazards. They are generally considered a "low-risk" choice for international travelers.