What medication is used for disembarkment syndrome?

Most medications for dizziness or motion sickness such as meclizine, dimenhydrinate, and scopolamine are not useful in MdDS. Anxiolytics may temporarily improve symptoms, with benzodiazepines likely to provide the most benefit. 4 Clonazepam is often preferred due to its longer half-life.



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There is no test to diagnose MdDS, so your ENT doctor will ask you questions about the symptoms and work to understand the patterns of your MdDS episodes. Your ENT doctor may prescribe certain medicines or vestibular therapy to help you find relief from your symptoms.

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I recommended to both patients several supplements, including CoQ10, 300 mg daily and 6 grams of omega-3 fatty acids. If magnesium is ineffective, medications, such as gabapentin (Neurontin), memantine (Namenda), and tizanidine (Zanaflex) can help without causing habituation seen with clonazepam.

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No underlying brain pathology was detected by magnetic resonance imaging of the brain. Magnesium glycinate and riboflavin were initi- ated to reduce MdDS symptom exacerbation by underlying migraines. These supplements were discontinued after 1 month due to worsening of motion sensation.

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In some cases, MdDS resolves on its own within a year. Prevention and symptom management for MdDS includes stress management, regular exercise, healthy eating, and rest. Clonazepam is an anti-seizure drug that is sometimes effective at low doses in treating symptoms of MdDS.

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MdDS is triggered by exposure to passive motion, whereas PPPD is triggered by events that disrupt balance function.

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In addition, individuals with MdDS have high comorbidities with migraine, increased visual sensitivity, and mood disorders, e.g., depression and anxiety (1, 2). The association with stress should also be further investigated, since it is known that stress can exacerbate MdDS symptoms (18).

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The symptoms usually disappear within hours, but in some people, and more frequently in women, symptoms can continue for months or years, causing fatigue, insomnia, headaches, poor coordination, anxiety, depression and an inability to work.

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