What over the counter OTC medications can I take and still be safe to fly?

NSAIDs (non- steroidal anti- inflammatory drugs) and analgesics acetaminophen (Tylenol) aspirin (Bayer's) ibuprofen (Advil/Motrin) naproxen (Naprosyn) Advil PM, Tylenol PM (Most “PM” medications contain diphenhydramine) Most OTC pain meds are safe to fly as long as the underlying condition is acceptable.



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Does the FAA have a list of prescription and over-the-counter drugs that pilots can and cannot take while flying?
  • Tranquilizers, such as but not limited to Valium, Librium, Ativan.
  • Most antidepressants. ...
  • Opiates, such as Morphine, Codeine, Lortab, Percodan, Oxycontin.
  • Muscle relaxants, such as Soma, Sonata, Flexeril.


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If you suffer from allergies, consider a non-sedating antihistamine instead, such as loratadine (Claritin®) or fexofenadine (Allegra). Claritin and Allegra do not have wait times (after the initial ground trial).

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Medication is sometimes prescribed on a temporary basis to treat the symptoms of a flying phobia, such as anxiety and nausea. These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax).

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These include any hormone-based drugs, like the contraceptive pill and some fertility medicines, and drugs used to prevent heart attack and stroke. Antihistamines should also not be used to help passengers sleep during a flight.

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It is recommended that medication be clearly labeled to facilitate the screening process. You may bring medically necessary liquids, medications and creams in excess of 3.4 ounces or 100 milliliters in your carry-on bag. Remove them from your carry-on bag to be screened separately from the rest of your belongings.

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All passenger items must undergo security screening. It is recommended that medication be clearly labeled to facilitate the screening process. You may bring medically necessary liquids, medications and creams in excess of 3.4 ounces or 100 milliliters in your carry-on bag.

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Never fly after taking a new medication for the first time until at least 48 hours have passed and no side effects are noted. As with alcohol, medications may impair your ability to fly—even though you feel fine. If you have questions about a medication, ask a healthcare provider. When in doubt, safety first—don't fly.

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Medications can be packed in a pill box. However, it is usually best to keep medicines in labeled containers provided by your pharmacist. TSA does not require medications to be in their original, labeled, prescription containers. However, using the original containers may limit delays or additional questioning.

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Firearms, ammunition, and fireworks are prohibited, as are all knives and safety razors (including pocket knives and Swiss Army knives). Straight razors and replacement blades for straight razors are also not allowed. Most tools also cannot be packed in carry-on luggage, as they have the potential to cause harm.

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Treat congestion before your trip
If you're congested from allergies or an upper respiratory infection, it's important to do what you can to resolve the congestion before you fly. Common treatments for congestion include antihistamines, decongestants, and nasal steroid sprays.

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As an example, a pilot using Sudafed to help control mild nasal congestion should clearly not continue flying while using it if that pilot develops an adverse reaction such as dizziness, headaches, or irregular heartbeats.

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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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Make sure to stand up and move around the plane when it is safe to do so. Avoid eating salty snacks and consuming alcohol and sedatives. Also, if you take blood pressure medication, don't forget to pack it in your carry-on so you can take it as needed.

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Flight anxiety medication
  • fluvoxamine (Faverin)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)


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