When should I take aspirin before a long flight?

Taking 75mg (a quarter of a normal 300mg tablet) some hours before your flight may reduce your chances of a DVT slightly (but remember that Aspirin can sometimes cause indigestion in people with a tendency to it, if in doubt ask your GP);



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Your GP will not be able to advise on the use of anticoagulants for flying as it is a specialist issue, so allow plenty of time to get an opinion from your specialist. Note: aspirin is not used to prevent DVT.

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Bajakian recommends you talk to your doctor before taking a flight longer than 4 to 6 hours. In some extremely high-risk cases, she may prescribe a course of low-dose anticoagulation medication for travel.

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Prevent Blood Clots During Travel
  1. Stand up or walk occasionally. ...
  2. Exercise your calf muscles and stretch your legs while you're sitting. ...
  3. Talk to your doctor about wearing compression stockings or taking medicine before departure if you have additional risk factors for blood clots.


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Most information about blood clots and long-distance travel comes from information that has been gathered about air travel. However, anyone traveling more than four hours, whether by air, car, bus, or train, can be at risk for blood clots.

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Research has shown that wearing compression socks during long-haul flights can significantly reduce the risk of developing blood clots and alleviate symptoms of leg fatigue and discomfort.

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What Are the Best—And Safest—Sleeping Pills for Flights?
  • Ambien. Ambien—the most powerful option on this list and the only one that requires a prescription—works as a sedative-hypnotic medication that slows your brain activity to make you feel very sleepy. ...
  • Tylenol PM. ...
  • Melatonin.


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Low-dose aspirin or baby aspirin (81 to 100 milligrams) has been used as a safe and cheap way to reduce the risk of cardiovascular diseases, heart attacks, strokes, and blood clots. Aspirin does this by thinning out the blood and preventing blood clots from forming, which may block arteries.

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It has been well recognized that a hypercoagulable state exists when a person is exposed to high altitude environment. This may manifest as early thromboembolic episodes, which may result in deep vein thrombosis (DVT) or acute pulmonary embolism (PE), which is a potentially fatal condition.

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