The city's most crime-ridden neighborhoods include Tor Bella Monaca, Romanina, San Basilio, and Corviale. In addition, certain Rome train stations, including Termini, are hubs for pickpockets in Rome, especially at night.
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Rome: Anywhere in “central” Rome is safe. Prati is known to be the safest area of Rome, and it is residential to many affluent Roman families. Hotels and apartments near the Vatican, Pantheon, Campo de' Fiori, and Piazza Navona are in ideal, safe locations as well.
3 to 5 days are enough for Rome. There's a lot to see in Rome and you could easily spend a week in the city seeing everything. 3 days is the absolute minimum you'll need but if you can stretch it a day or two further you'll be able to see most of the city and the surrounding area.
Is it safe to walk in the streets of Rome? A moderate risk of being robbed, getting attacked, or assaulted. Most of the time, a tourist won't be affected at all by these crimes. It's also completely safe to walk around Rome during the day and there's a moderate risk in some areas of the city at nighttime.
The Vatican has a dress code that some travellers might not be aware of when visiting. Luckily if you're planning on wearing jeans to the Vatican, you definitely can! When you plan to visit, it's best to keep your knees and shoulders covered. And for footwear, you will need flat shoes, not flip-flops or casual sandals.
However, Tuesdays and Thursdays usually see fewer tourists around most of the attractions in the Vatican. It is better to avoid Wednesdays and weekends if you're on a tight schedule because the city has a tendency to be a bit busier on those days.
Rome: Anywhere in “central” Rome is safe. Prati is known to be the safest area of Rome, and it is residential to many affluent Roman families. Hotels and apartments near the Vatican, Pantheon, Campo de' Fiori, and Piazza Navona are in ideal, safe locations as well.