Tuscany is served by two main international airports, but Florence Airport (FLR), also known as Amerigo Vespucci, is the most centrally located and closest to the heart of the region. It is situated just 4 km from Florence's city center, making it the ideal choice if your base is the regional capital. However, Pisa International Airport (PSA), also known as Galileo Galilei, is the larger of the two and often handles the bulk of international and low-cost flights (like Ryanair) in 2026. While Pisa is about 80 km from Florence, the high-speed "PisaMover" shuttle and frequent train connections make it a very convenient entry point. If you are staying in the southern or coastal parts of Tuscany, Pisa is actually more accessible. For travelers coming from outside Europe in 2026, many choose to fly into Rome (FCO) and take the 90-minute high-speed Frecciarossa train directly into Tuscany for a wider selection of flight times.