The most frequently used antihistamines to treat motion sickness include cyclizine, dimenhydrinate, meclizine, and promethazine (oral and suppository); nonsedating antihistamines appear to be less effective.
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The first is antihistamines, both prescription and over-the-counter. These are the most commonly used medications for motion sickness, and they're available in any drug store and in many supermarkets. Cyclizine (Marezine) and dimenhydrinate (Dramamine) are two major ones. Make sure to read the drug labels, though.
People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.
Make sure your pre-travel diet includes plenty of fiber, which makes stools softer and more comfortable to pass. Foods high in fiber include many fruits, like apples (with the skin), raspberries, and pears; beans; and whole-grain foods such as bran cereal.
People who do not travel often may get used to movement during a trip lasting several days. Even those who travel often may find that symptoms get better as they are more often exposed to motion. However, people who get anxious before a journey often have worsened symptoms of motion sickness.
A weakened immune system“When you travel,” says Dr. Oza, “your usual routines are disrupted. You may not be sleeping as well as you do at home, and your eating habits change when you're away. You may be staying up later, consuming more alcohol and getting less exercise than usual.