Children's liquid Benadryl can be used for small dogs using the same dosage. Avoid the adult formula of liquid Benadryl, as this often contains alcohol, which is toxic to dogs.
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There is no clear evidence that any one antihistamine works better than another, so other factors can be considered when choosing an allergy medication.
In living animals, hyperactivity, depression, hypersalivation, tachypnea, and tachycardia are the most common signs reported with ethanolamine-based antihistamines, usually occurring within 1 h of exposure (10). With overdose, dogs may also exhibit mydriasis, dry mucous membranes, disorientation, and fever (10).