Which is better for flight anxiety Ativan or Xanax?

Ativan and Xanax are both benzodiazepines used for the treatment of anxiety, and both are equally effective for this use. The differences are: Xanax has a quicker onset of effect, but a shorter duration of action (4 to 6 hours) compared with Ativan's 8 hours.



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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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Benzodiazepines, such as clonazepam, help reduce anticipatory anxiety and can enable a patient to manage fear and anxiety during the initial stages of exposure therapy [15].

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Flight anxiety medication
  • fluvoxamine (Faverin)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)


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When taken prior to the flight Benzodiazepines such as alprazolam (Xanax), lorazepam (Ativan), clonazepam (Klonopin), and diazepam (Valium) are common options to reduce anxiety of flying. These medications decrease the person's reflective function.

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Benzodiazepines are only advised for the short-term use for a crisis in generalised anxiety disorder in which case they are not fit to fly.

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Xanax, a member of the same pharmaceutical family (benzodiazepines) as diazepam, is a strong one. Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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Deep breathing is known to trigger a comfort response and will help prevent hyperventilation. Reading a book or listening to a good podcast can refocus your mind and attention. Distracting yourself from the fact that you are flying can be a great way to keep calm if you're a nervous flyer..

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Medication is sometimes prescribed on a temporary basis to treat the symptoms of a flying phobia, such as anxiety and nausea. These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax).

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Over-the-counter medicines
  • Diarrhea medicine (Imodium or Pepto-Bismol)
  • Antacid.
  • Antihistamine.
  • Motion sickness medicine.
  • Cough drops, cough suppressant, or expectorant.
  • Decongestant.
  • Pain and fever medicine (acetaminophen, aspirin, or ibuprofen)
  • Mild laxative.


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Guide for Aviation Medical Examiners: Pharmaceuticals, Do Not Issue Do Not Fly— from angina to weight-loss medications, including these psychiatric medications: antidepressants (certain SSRIs may be allowed – see SSRI policy) antianxiety drugs – e.g.: alprazolam (Xanax) antipsychotics.

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