Yes, you can absolutely get a taxi at 3:00 AM in Rome, as the city operates on a 24/7 transportation cycle. However, you cannot simply "hail" a cab on the street in Rome as easily as in New York; you must either go to a designated "Taxi Rank" (located near major landmarks like Termini Station, Largo Argentina, or Piazza Venezia) or book one via an app. In 2026, the FreeNow and itTaxi apps are the standard for locals, while Uber is also widely used to summon official "Uber Taxi" cabs. Be prepared for a "Night Supplement" fee of approximately €6.50 added to the base meter for trips between 10:00 PM and 6:00 AM. If you are heading to Fiumicino Airport (FCO) at this hour, it is highly recommended to book your ride at least 20 minutes in advance to ensure a driver is dispatched to your specific alley or hotel entrance, as Rome's narrow streets can make 3:00 AM pickups slightly more complex for drivers to navigate.