How do you prevent sinus pressure when flying?

Spray Afrin nasal decongestant spray twice into each nostril one hour prior to flying. Begin taking a decongestant, like Sudafed, one hour before the flight. Both of these medications can be purchased over-the-counter in a drug store.



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If suffering from a sinus infection while flying, you may experience severe sinus pressure and pain. We recommend avoiding air travel when possible if you have a sinus infection. By treating the root cause of your sinus pressure and pain, you can avoid a lifetime of painful flights.

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Some studies suggest that the cabin pressure changes in the airplane, which are more pronounced during takeoff and landing, affects the head and sinuses in a way that triggers a headache. Another possible explanation for AHs is a fear of flying, which can cause stress and anxiety and subsequently trigger a headache.

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Treat congestion before your trip
If you're congested from allergies or an upper respiratory infection, it's important to do what you can to resolve the congestion before you fly. Common treatments for congestion include antihistamines, decongestants, and nasal steroid sprays.

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When the plane changes elevation during descent and ascent the sinuses must equilibrate to match the air pressure in the cabin but when the sinuses and eustachian tubes are blocked equilibration can be an issue. The pain occurs because of the restriction of air flow causing pressure in our sinuses.

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If you suffer from allergies, consider a non-sedating antihistamine instead, such as loratadine (Claritin®) or fexofenadine (Allegra). Claritin and Allegra do not have wait times (after the initial ground trial).

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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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It is not recommended to fly with acute intracranial hypertension because the conditions in the plane can worsen your condition and cause excruciating pain. If you have chronic or benign intracranial hypertension, you might be able to fly if your condition is under control.

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Pain Killers and Anti-Febrile Drugs These medications are commonly used to treat pain, fever, or headaches. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and paracetamol may be taken whilst flying.

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Aspirin? Taking 75mg (a quarter of a normal 300mg tablet) some hours before your flight may reduce your chances of a DVT slightly (but remember that Aspirin can sometimes cause indigestion in people with a tendency to it, if in doubt ask your GP);

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Flight anxiety medication
  • fluvoxamine (Faverin)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)


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You can help send a signal to your brain that it's time to sleep by using melatonin. Melatonin is a more natural alternative to a prescription sleep aid, and it's available at drugstores over the counter. Maloney travels with Sleep Now, a brand that features melatonin and chamomile to help travelers relax.

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Medicines according to carry-on luggage rules Passengers can take generally available medicines, i.e. those sold without a prescription, to the plane. These include eye drops, nasal sprays, cough syrups and throat lozenges. There should be no problem with transporting them, and you can take more than 100 ml with you.

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