How long before a flight should I take Benadryl?

How long before flight should I take Benadryl? If you're taking antihistamines, decongestants, or over-the-counter pain medicine like ibuprofen or acetaminophen, it's important to take your medication at least an hour before your flight so it has time to work before your plane takes off.



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Yes, Benadryl is an antihistamine that causes drowsiness in most people. Some people use Benadryl for this side effect if they have trouble sleeping (insomnia), but this is not recommended long-term. The drowsy or sedation effect typically lasts about 8 hours, but may persist into the next day if taken at night.

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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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If you suffer from allergies, consider a non-sedating antihistamine instead, such as loratadine (Claritin®) or fexofenadine (Allegra). Claritin and Allegra do not have wait times (after the initial ground trial).

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Medication is sometimes prescribed on a temporary basis to treat the symptoms of a flying phobia, such as anxiety and nausea. These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax).

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Treat congestion before your trip
If you're congested from allergies or an upper respiratory infection, it's important to do what you can to resolve the congestion before you fly. Common treatments for congestion include antihistamines, decongestants, and nasal steroid sprays.

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