In 2026, the train journey from Florence (Firenze Santa Maria Novella) to the Cinque Terre villages (typically starting at La Spezia) takes between 1.5 to 3 hours, depending on whether you catch a high-speed or regional train. Most travelers take a regional train from Florence to Pisa or Empoli, then transfer to a train heading to La Spezia Centrale. From La Spezia, you hop on the "5 Terre Express" which takes only minutes to reach each village. A supportive peer "travel hack": look for the rare direct Intercity trains that can cut the travel time down significantly, though they only run a few times a day. If you are doing this as a day trip in 2026, aim for the 7:00 AM departures to maximize your time. Total distance is only about 160 km, but the frequency of stops and the necessary transfer at La Spezia mean you should budget at least 2.5 hours for a stress-free transition from the city to the coast.