Should I take Benadryl before flying?

If Benadryl® is the only medicine you find that can provide relief for your cold, allergy, or sleep symptoms and you feel you cannot give it up, you should wait at least five (5) half-lives before getting in the cockpit. Benadryl's® half-life is quite long, up to 10 hours.



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For patients taking dimenhydrinate or diphenhydramine for motion sickness: Take this medicine at least 30 minutes or, even better, 1 to 2 hours before you begin to travel.

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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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If you have any allergy or cold-related symptoms, make sure you take an antihistamine or decongestant spray at least 30-45 minutes before your flight. Following this method can help alleviate any additional sinus pressure.

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Medication is sometimes prescribed on a temporary basis to treat the symptoms of a flying phobia, such as anxiety and nausea. These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax).

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Yes, Benadryl is an antihistamine that causes drowsiness in most people. Some people use Benadryl for this side effect if they have trouble sleeping (insomnia), but this is not recommended long-term. The drowsy or sedation effect typically lasts about 8 hours, but may persist into the next day if taken at night.

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Take a melatonin pill. That's the hormone that our bodies use to put us to sleep naturally. Pop the pill a few hours before the flight.

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As a general precaution, however, Dr. Varga does not recommend taking either melatonin or a sleeping pill for the first time on a plane, given that both may occasionally cause adverse effects in some people. (And it's best not to find out that you're one of those people while you're trapped at 30,000 feet.)

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The most frequently used antihistamines to treat motion sickness include cyclizine, dimenhydrinate, meclizine, and promethazine (oral and suppository); nonsedating antihistamines appear to be less effective.

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Try holding your breath and then breathing deeply, or better still, force yourself to breathe out for as long as you can and then take a long, deep breath. Seif and Farchione both recommended taking deep breaths, since this triggers the calming response and can help to prevent hyperventilation.

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For example, deep breathing or meditation during take-off, landing or turbulence can reduce your symptoms of anxiety. You can also learn to “talk back” to negative thoughts about flying when they arise.

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