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What does flying do to the brain?

Lower levels of inspired oxygen result in increases in intracranial pressure and can subsequently compromise perfusion of some brain regions.



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It is not recommended to fly with acute intracranial hypertension because the conditions in the plane can worsen your condition and cause excruciating pain. If you have chronic or benign intracranial hypertension, you might be able to fly if your condition is under control.

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For those who are already nervous fliers, there is perhaps some more bad news. “Anxiety levels can increase with hypoxia,” explains Valerie Martindale, president of the Aerospace Medical Association at King's College London. Anxiety is not the only aspect of mood that can be affected by flying.

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Plane travel makes jet lag worse because your body moves much faster than your brain and circadian rhythms can process the time change. Other aspects of travel can also contribute to jet lag and may make symptoms worse: Long periods of sitting on a plane. Lack of oxygen and decreased air pressure in the airplane cabin.

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Some studies suggest that the cabin pressure changes in the airplane, which are more pronounced during takeoff and landing, affects the head and sinuses in a way that triggers a headache.

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While many people believe that recirculated, germy air is the main culprit of illness after a plane ride, the real reason why flying can cause us to get sick is from low humidity. When you're soaring through the sky, the high elevations cause the humidity level in the airplane cabin to decrease.

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One in three people said that the most stressful part of travelling was during the flight, with a further 35% saying they found landing the most stressful. Boarding, finding your seat on the plane and the flight itself all came at the bottom of the list, making them the least stressful moments whilst travelling.

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Sitting down in a tight seat for 13+ hours can sometimes lead to circulation issues, including swelling in the feet. According to The Healthy, the chance of your body forming blood clots increases when blood isn't moving correctly, such as when onboard a long-haul flight.

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When flying at altitude, the reduced air pressure leads to an element of hypoxia meaning less oxygen is getting to your brain. This can lead to a decrease in cognitive performance and reasoning (though usually, this is only a mild effect in the pressurised cabin) more noticeable in the very young and older people.

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At high altitudes, cerebral hypoxia triggers the upregulation of VEGF. In turn, the VEGF increases capillary permeability and contributes to cerebral edema. Note, however, that brain swelling attributable to ascent to high altitudes may occur without any associated symptoms.

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The main aspect of in-flight health that most of us will encounter is tiredness and changes to circadian rhythms. Flying often involves getting up at unsociable hours, inadequate sleep and messing up the body clock — all of which leave us more susceptible to being hit nastily by any bugs that may be floating about.

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This increases the risk of ischemic stroke, which takes place when an artery in the brain becomes blocked by a blood clot. Risk of developing a clot has been found to be increased during and after air travel by many research studies. In fact, clot risk may be elevated by as much as 26% for longer flight times.

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Aircraft noise pollution disrupts sleep, children's education and could increase cardiovascular risk. Airports can generate water pollution due to their extensive handling of jet fuel and deicing chemicals if not contained, contaminating nearby water bodies.

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Jet lag is a temporary sleep disorder, but not temporary enough for many travelers. If you're flying from San Francisco to Rome for a 10-day trip, for example, it may take six to nine days to fully recover. That's because it can take up to a day for each time zone crossed for your body to adjust to the local time.

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The Airport and Airplanes are Full of Germs Airplanes are just as dirty. Studies have shown bacteria and viruses living on armrests, seat belts, window shades, tray tables, toilet handles, and more for DAYS.

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Air Pressure
Air is actually less oxygen-dense at higher altitudes. Meaning the higher you go, the less oxygen will be available to you. While you may not consciously notice any trouble breathing, you are likely to feel drained and tired once you land at your destination.

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“For the most part, pilots fear those things they cannot control,” Smith wrote. “We are less afraid of committing a fatal error than of finding ourselves victimised by somebody else's error or else at the mercy of forces impervious to our skills or expertise.”

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Some fliers are worried about being in an enclosed space for too long, others dislike heights, and a select group is terrified they might accidentally open a plane door mid-flight. Furthermore, some passengers are worried about germs and viruses and others are just anxious that they might feel anxious on a plane.

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Jet lag symptoms usually occur within a day or two after traveling across at least two time zones. Symptoms are likely to be worse or last longer the farther you travel. This is especially true if you fly east. It usually takes about a day to recover for each time zone crossed.

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Aerotoxic syndrome relates to ill-health effects associated with breathing contaminated air in an airliner cabin. Researchers have associated aerotoxic syndrome with exposure to substances such as engine oil and hydraulic fluid.

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