The most common illness associated with cruise ships in 2026 remains Norovirus, a highly contagious gastrointestinal virus that causes vomiting and diarrhea. Because cruise ships are "closed environments" where thousands of people share dining areas and facilities, the virus can spread quickly if an infected person boards. In early 2026, several outbreaks have been reported, including on major lines departing from Florida. While the cruise industry uses incredibly high-grade medical sanitation protocols, the "stomach bug" remains a persistent challenge. To stay healthy, the CDC and cruise lines emphasize frequent handwashing with soap and water, as hand sanitizer is less effective against Norovirus than it is against respiratory viruses like COVID-19 or the common flu.