The choice between Interlaken and Grindelwald as a base for your Swiss adventure in 2026 depends entirely on your travel priorities. Interlaken is the ultimate logistical hub; it sits between Lake Thun and Lake Brienz and offers two major train stations (Ost and West). It is "better" if you plan to explore the wider Bernese Oberland region, including Day trips to Bern, Lucerne, or Thun, as you won't have to navigate mountain trains every morning. It also has more "big city" amenities like large supermarkets and a wider variety of nightlife. However, Grindelwald is arguably "better" for a true Alpine experience. It is a "glacier village" located directly at the foot of the Eiger North Face. If your primary goal is hiking, skiing, or taking the Eiger Express to Jungfraujoch, Grindelwald saves you 30-40 minutes of transit time each way. While Grindelwald is more "touristy" and can feel crowded, waking up to the literal sight of 4,000-meter peaks is a sensation Interlaken cannot match. Ultimately, choose Interlaken for convenience and variety, but choose Grindelwald for breathtaking views and immediate mountain access.