Can I take aspirin before a long haul flight?

Taking aspirin to prevent blood clots when traveling is not recommended. If you take aspirin for other reasons, check with your doctor.



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Taking aspirin to prevent blood clots when traveling is not recommended. If you take aspirin for other reasons, check with your doctor.

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The plasma half-life of aspirin is only 20 minutes; however, because platelets cannot generate new COX, the effects of aspirin last for the duration of the life of the platelet (˜10 days). After a single dose of aspirin, platelet COX activity recovers by ˜10% per day as a function of platelet turnover.

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What Are the Best—And Safest—Sleeping Pills for Flights?
  • Ambien. Ambien—the most powerful option on this list and the only one that requires a prescription—works as a sedative-hypnotic medication that slows your brain activity to make you feel very sleepy. ...
  • Tylenol PM. ...
  • Melatonin.


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Over-the-counter medicines
  • Diarrhea medicine (Imodium or Pepto-Bismol)
  • Antacid.
  • Antihistamine.
  • Motion sickness medicine.
  • Cough drops, cough suppressant, or expectorant.
  • Decongestant.
  • Pain and fever medicine (acetaminophen, aspirin, or ibuprofen)
  • Mild laxative.


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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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Wear compression socks Compression socks work wonders on the plane! These socks apply a gentle squeeze to your legs, and according to the NHS, they help maintain blood flow and stop it pooling in the lower legs. They do a fantastic job of preventing swelling and reducing discomfort during long flights.

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Most information about blood clots and long-distance travel comes from information that has been gathered about air travel. However, anyone traveling more than four hours, whether by air, car, bus, or train, can be at risk for blood clots.

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